Automobile plays an important role in the fugitives' escape.
Michael Scofield
1992-1993 Honda Accord LX
- License: 64S 6325
- Colour: Gray
- Blown up by Michael as a part of his escape plan
1983-1987 Ford LTD Crown Victoria
- License Plate: AE9268
- Colour: Dark Blue
- Crashed with Mahone's Ford
1997-1998 Ford Escort LX
- License Plate: 24S 3437
- Colour: Silver
Alexander Mahone
Ford Crown Victoria
- License Plate: Unknown
- Colour: White
- Crashed with Michael's Sedan
Brad Bellick
1986 Chevrolet Caprice Classic
- License Plate: None
- Colour: Brown
Fernando Sucre
1980 Chevrolet El Camino
- License Plate: Unknown
- Colour: Brown
- Stolen by Sucre
1952 Ural
- License Plate: Unknown
- Colour: Black
- Originally belongs to his cousin Petey, who unsuccessfully tried to hold him back.
1973 Volkswagen Beetle
- License Plate: FHX29 94
- Colour: Light Blue
- Originally belongs to Old Mexican Man, who gave him the car as a present to aid him to find Maricruz
John Abruzzi
1998-2002 Lincoln Town Car
- License Plate: Unknown
- Colour: Black
Chicago Police
2006 Ford Crown Victoria LX
- License Plate: Varies
- Colour: White and Blue
Coyote
1987-1991 Ford F-250 Pickup
- License Plate: Unknown
- Colour: Dark Blue
Marvin Gudat
2005-2007 Jeep Grand Cherokee Laredo
- License Plate: 25V 1680
- Colour: White
- After Gudat was killed by T-Bag, T-Bag took his car
Hunter
1987-1991 Jeep Grand Wagoneer
- License Plate: Unknown
- Colour: White
- Car was hijacked by Abruzzi, Michael, Lincoln, Sucre and C-Note
Pennsylvania State Trooper
Unknown Model of Motorcycle
- License Plate: Varies
- Colour: White
Jerry Curtin
1985 Oldsmobile Cutlass Cruiser Wagon
- License Plate: ATZ 4938
- Colour: Light Green
- Taken by T-Bag after he fatally wounded him
The Gravedigger
Unknown '66
- License Plate: Unknown
- Colour: Red